This is a collection of sixteen essays by a diverse group of international scholars that offers a wide-ranging and contemporary perspective on the major aspects of Christian Wolff’s ethics. The volume focuses on Wolff’s German Ethics, arguably his most important and influential text on moral philosophy, but many of the chapters also consider the development of the basic tenets of Wolff’s moral theory in his later Latin writings. The contributions cover a range of topics, including the systematic structure of the (...) text itself and the relation between Wolff’s ethics and the preceding natural law tradition. Many chapters pay special attention to the core concepts of Wolff’s moral philosophy, such as obligation, perfection, the highest good, and happiness. Other notable topics include Wolff’s conception of moral judgment and moral education, as well as the role of psychology and anthropology in his ethical thought. The volume also contains discussion of the influence of Wolff’s ethics on subsequent figures such as C.A. Crusius, G.F. Meier, and Kant. As a whole, the volume seeks to establish the importance of Wolff’s German Ethics within the history of ethics as well as inspire others to engage with his thought. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

John F. Post argues that physicalistic materialism is compatible with a number of views often deemed incompatible with it, such as the objectivity of values, the irreducibility of subjective experience, the power of the metaphor, the normativity of meaning, and even theism.

In his “Theology and Falsification” Professor Antony Flew challenges the sophisticated religious believer to state under what conceivable occurrences he would concede that there really is no God Who loves mankind: ‘Just what would have to happen not merely to tempt but also, logically and rightly, to entitle us to say “God does not love us” or even “God does not exist”? I therefore put…the simple central questions, “What would have to occur or to have occurred to constitute for you (...) a disproof of the love of, or of the existence of, God”?’. (shrink)

Planctomycetes, Verrucomicrobia and Chlamydia are prokaryotic phyla, sometimes grouped together as the PVC superphylum of eubacteria. Some PVC species possess interesting attributes, in particular, internal membranes that superficially resemble eukaryotic endomembranes. Some biologists now claim that PVC bacteria are nucleus‐bearing prokaryotes and are considered evolutionary intermediates in the transition from prokaryote to eukaryote. PVC prokaryotes do not possess a nucleus and are not intermediates in the prokaryote‐to‐eukaryote transition. Here we summarise the evidence that shows why all of the PVC traits (...) that are currently cited as evidence for aspiring eukaryoticity are either analogous (the result of convergent evolution), not homologous, to eukaryotic traits; or else they are the result of horizontal gene transfers. (shrink)

This article argues against the present government educational monopoly and explains why taxpayers should not be forced to subsidize what is, in effect, anestablishment of a "religion" of secularism. It argues that parents in justice have a right to have the wherewithal to have genuine choice in the education of their children.

With the increasing amount of software devoted to industrial automation and process control, it is becoming more important than ever for systems to be able to explain their behavior. In some domain...

The essays in this book engage with the broad range of Jürgen Habermas' work including politics and the public sphere, nature, aesthetics, the linguistic turn and the paradigm of intersubjectivity.

In this incisive study, John F. X. Knasas grounds the ideal of tolerance in Aquinas’s natural law ethics and connects the virtue of civic tolerance to the concept of being. If God is the source of being, argues Knasas, then we are the articulation of being, and it is in this capacity that we recognize our bond with other people and thus acknowledge our duty to be tolerant of one another. An important contribution to practical metaphysics and the philosophical (...) foundations of political theory, _Thomism and Tolerance_ will appeal to philosophy scholars and students at the undergraduate and graduate level. (shrink)

This article explores the influence that the proportion of women in a department has on hiring decisions in the field of psychology. A sample of advertisers from the APA Monitor was asked to identify the gender of the candidate hired. Hiring patterns were the same for men and women hirers in nonacademic organizations, as each favored male candidates. In academic hiring, women candidates were favored in departments with moderate female representation. This finding counters claims that women are hired by departments (...) with few women in response to affirmative action. Rather, the presence of moderate numbers of women influences hiring decisions that promote women's opportunities. (shrink)

John F. Henry is an eminent economist who has made important contributions to heterodox economics drawing on Adam Smith, Karl Marx, Thorstein Veblen, and John Maynard Keynes. His historical approach offers radical insights into the evolution of ideas (ideologies and theories) giving rise to and/or induced by the changes in capitalist society. Essays collected in this festschrift not only evaluate John Henry's contributions in connection to Marx's and Veblen's theories, but also apply them to the socio-economic issues (...) in the 21st century. In Part I leading heterodox economists in the traditions of Marxism, Post Keynesianism, and Institutionalism critically examine Marx's and Veblen's theoretical frameworks (and their connections to each other) that have become the foundations of heterodox economics. Chapters in Part II showcase alternative theoretical explanations inspired by Marx, Veblen, and Henry. Topics in this Part include financial crisis, financialization, capital accumulation, economics teaching, and the historical relationship between money and class society. Part III is devoted to John Henry's heterodox economics encapsulated in his "farewell" lecture, interview, and bibliography. Essays in this book, individually and collectively, make an important point that the history of economic thought (or historical analysis of economic theory and policy) is an integral part of developing heterodox economics as an alternative theoretical framework. Anyone who is troubled by the recurring failure of capitalism as well as mainstream economics will find this book well worth reading. (shrink)

This article explores three literature bases in some depth: strategy, stakeholder/ social issues, and the newly emergingworks in reputation. The focus is on the potential research and practical overlaps that exist in these literatures. A model of reputation is developed that highlights these research opportunities for scholars in all three endeavors. Amodel of reputation formation is developed that can be used for further study and action. Throughout the analysis, various research avenues are suggested for active consideration.

Medical and nursing personnel have an obligation to provide the medication necessary for every patient’s pain relief. This includes patients whose life-supporting mechanical ventilation is being removed, who may not exhibit traditional signs of pain or dyspnea. The purpose of this paper is not to argue a position on withdrawing life support. Rather, it argues that nurses and physicians have an obligation to provide pain-relieving medication, such as opiates, when life support is removed, to ensure that those entrusted to their (...) care do not experience pain or significant distress. This is based on the principle of double effect, by which two actions, one intended and one unintended, may be permissible if there is a proportionate reason. The goal in these situations is never to hasten death intentionally but to make patients’ pain and suffering tolerable as a matter of compassionate and loving care. (shrink)

Preface par PIERRE FORCE I have a very precise recollection of my first encounter with John Boi- tano. It was during the spring semester of 1988, ...

No healthcare issue has generated as much ethical debate on the relationship between the individual and society as HIV Infection. In this debate, an appeal is most often made to such principles as autonomy and confidentiality to protect individuals who are HIV positive or who have AIDS from an invasion of privacy thought to be justified by society's need for information. In the first years, this emphasis on the protection of the individual was essential. Even today, there are risks in (...) disclosing one's HIV status. However, as more and more persons become Infected, live longer, and move within the healthcare industry for non-HIV related care, as both patients and healthcare workers, the terms of the debate need to be redefined. (shrink)